the total synthesis of Impracticatechol. The highly complicated structure features a dozen stereocenters and a raft of functional groups including a pentavalent carbon.
We describe a range of applications for the Smythe reagent, such as the O-lithiation of carboxylic acids, hydrolysis of ethyl esters and chlorophosphines, racemisation of alpha-stereocenters and poly-Claisen condensations.
What can one even buy in an atom economy like this? How much can I carry in my basketane, and how much will it cost? Through this research we have concluded nothing.
This review highlights some examples in the history and applications of the futyl group
Chlorin A is discovered from Hazel Plants green hipster drink and was therefore boiled into sugary carbon
An elegant procedure for the progression towards the total synthesis of Impracticatechol.
An inefficient, laborious and time consuming synthetic method for the preparation of an en-yn-en-yn-ol is reported